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HAPE3D—a new constructive algorithm for the 3D irregular packing problem
Xiao LIU,Jia-min LIU,An-xi CAO,Zhuang-le YAO
《信息与电子工程前沿（英文）》 2015年 第16卷 第5期 页码 380-390 doi: 10.1631/FITEE.1400421
关键词： 3D packing problem Layout design Simulation Optimization Constructive algorithm Meta-heuristics
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《医学前沿（英文）》 2018年 第12卷 第3期 页码 340-349 doi: 10.1007/s11684-017-0565-0
Benralizumab is a monoclonal antibody that targets interleukin-5 receptor α to deplete blood eosinophils and improve the clinical outcomes of allergic asthma. We conducted a meta-analysis to evaluate the safety and efficacy of different doses of benralizumab in patients with eosinophilic asthma. All randomized controlled trials involving benralizumab treatment for patients with eosinophilic asthma, which were searched in PubMed, Embase, and the Cochrane Library published until January 2017, as well as the rate of asthmatic exacerbation, pulmonary functionality, asthma control, quality of life scores, and adverse events were included. Randomized-effect models were used in the meta-analysis to calculate the pooled mean difference, relative risks, and 95% confidence intervals. Five studies involving 1951 patients were identified. Compared with the placebo, benralizumab treatment demonstrated significant improvements in the forced expiratory volume in 1?s (FEV1), Asthma Quality of Life Questionnaire scores, decreased asthmatic exacerbation and Asthma Control Questionnaire-6 (ACQ-6) scores. Benralizumab treatment was also not associated with increased adverse events. These findings indicated that benralizumab can be safely used to improve FEV1, enhance patient symptom control and quality of life, and reduce the risk of exacerbations and ACQ-6 scores in patients with eosinophilic asthma. Furthermore, our meta-analysis showed that benralizumab with 30 mg (every eight weeks) dosage can improve the health-related quality of life and appear to be more effective than 30 mg (every four weeks) dosage. Overall, data indicated that the optimal dosing regimen for benralizumab was possibly 30 mg (every eight weeks).
关键词： benralizumab anti-interleukin-5 monoclonal antibody eosinophilic asthma meta-analysis
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《医学前沿（英文）》 2016年 第10卷 第2期 页码 191-203 doi: 10.1007/s11684-016-0450-2
The relationship between telomere length and cancer survival has been widely studied. To gain a deeper insight, we reviewed the published studies. A total of 29 studies evaluated telomere length in the peripheral blood; 22 studies evaluated telomere length in the tumor tissue. First, in the peripheral blood studies, for solid tumor patients with shortened telomere length, the combined hazard ratios (HRs) for mortality and tumor progression were 1.21 (95%CI, 1.10–1.32) and 1.71 (95%CI, 1.37–2.13), respectively. Meanwhile, in hematology malignancy, the combined HRs for mortality and tumor progression were 2.83 (95%CI, 2.14–3.74) and 2.65 (95%CI, 2.18–3.22), respectively. Second, in the studies that use tumor tissue, for patients with shortened telomeres, the combined HRs for mortality and tumor progression were 1.26 (95%CI, 0.95–1.66) and 1.65 (95%CI, 1.26–2.15), respectively. In the studies that calculate the telomere length ratios of tumor tissue to adjacent normal mucosa, for patients with lower telomere length ratios, the combined HRs were 0.66 (95%CI, 0.53–0.83) and 0.74 (95%CI, 0.41–1.32) for mortality and tumor progression, respectively. In conclusion, shortened telomere in peripheral blood and tumor tissue might indicate poor survival for cancer patients. However, by calculating the telomere length ratios of tumor tissue to adjacent normal mucosa, the lower ratio might indicate better survival.
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《医学前沿（英文）》 2013年 第7卷 第3期 页码 354-366 doi: 10.1007/s11684-013-0257-3
Due to the implementation of directly observed treatment strategy (DOTS), China has made a significant achievement in tackling the tuberculosis (TB) epidemic in the 1990s. However, only half of regions in China met or exceeded the 85% rate of treatment success target. The aim of the present study is to summarize the treatment outcomes of smear-positive pulmonary TB in the mainland of China in the past decade using meta-analysis based on systematic review of published observational studies. A total of 50 eligible articles (58 studies) were identified and included in this study. The summarized treatment success rates were 93.9% (95% CI, 92.8%–94.7%) for new cases and 85.4% (95% CI, 83.0%–87.6%) for previously treated cases, and the summarized cured rate were 92.2% (95% CI, 90.9%–93.3%) and 81.2% (95% CI, 79.1%–83.1%), respectively. A remarkable increase of rates for treatment success and cure was observed in the 1990s. After 2000, the summarized treatment outcomes were tending towards stability. In addition, geographic areas, type of the data and administrative level of the hospital were also found to influence the estimates of the treatment outcomes. Results of the present study clearly show, in general, that the pulmonary TB treatment achieved significant success in the past decade in the mainland of China. However, it needs to be further strengthened in the central and west areas.
An update and cumulative meta-analysis
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《医学前沿（英文）》 2014年 第8卷 第2期 页码 241-249 doi: 10.1007/s11684-014-0328-0
Approximately 70% of newly diagnosed bladder tumors are non-muscle invasive bladder cancer (NMIBC). NMIBC accounts for approximately 80% of total bladder cancer cases. Bacillus Calmette-Guérin (BCG) instillation and maintenance is considered as the standard adjuvant treatment for superficial bladder cancer. A number of randomized studies have focused on the benefit of maintenance therapy following initial BCG induction. To provide further insights into the effect of intravesical instillation on recurrence in patients with NMIBC, we analyzed this relationship by conducting an updated detailed meta-analysis. Evidence suggested that adjuvant intravesical BCG with maintenance treatment is significantly effective for the prophylaxis of tumor recurrence in patients with NMIBC.
关键词： non-muscle invasive bladder cancer bacillus Calmette-Guérin (BCG) meta-analysis
Machine perfusion versus cold storage of livers: a meta-analysis
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《医学前沿（英文）》 2016年 第10卷 第4期 页码 451-464 doi: 10.1007/s11684-016-0474-7
Different organ preservation methods are key factors influencing the results of liver transplantation. In this study, the outcomes of experimental models receiving donation after cardiac death (DCD) livers preserved through machine perfusion (MP) or static cold storage (CS) were compared by conducting a meta-analysis. Standardized mean difference (SMD) and 95% confidence interval (CI) were calculated to compare pooled data from two animal species. Twenty-four studies involving MP preservation were included in the meta-analysis. Compared with CS preservation, MP can reduce the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and hyaluronic acid (HA) and the changes in liver weight. By contrast, MP can enhance bile production and portal vein flow (PVF). Alkaline phosphatase (ALP) levels and histological changes significantly differed between the two preservation methods. In conclusion, MP of DCD livers is superior to CS in experimental animals.
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《医学前沿（英文）》 2017年 第11卷 第2期 页码 191-202 doi: 10.1007/s11684-017-0512-0
Primary hepatic carcinoma (PHC) is a common malignant tumor in China. Cancer is comprehensively treated with various therapeutic regimes, including traditional Chinese medicine (TCM). TCM has been widely used to improve the quality of life, delay the time of cancer progression, and prolong the median survival time. This systematic review with meta-analysis aimed to assess the effect of TCM combined with Western therapy on primary hepatic carcinoma. A comprehensive literature search was conducted in six databases, including CNKI, VIP, Wan-Fang Database, CBM, PubMed, and Cochrane library. A total of 44 randomized controlled trials (RCTs) involving 3429 participants suffering from PHC were selected. Meta-analysis results indicated that the overall effect of TCM and Western integrative treatment on PHC was higher than that of Western intervention alone, which can postpone tumor recurrence and metastasis and prolong the overall survival time of patients with PHC. Although the obtained evidence remained weak because of the poor methodological quality of the included studies, this review provided relevant data supporting the efficacy and safety of TCM combined with Western therapies. In future research, individual RCT studies should incorporate accepted standards for trial design and reporting, proper outcome indicators according to international standards, blinding in allocation concealment, and valid follow-up periods.
关键词： traditional Chinese medicine primary hepatic carcinoma meta-analysis
Research and Practice of Meta-synthesis Management for the Government-led Urban Complex Construction
Ru-gui Chen,Jia-meng Chen
《工程管理前沿（英文）》 2014年 第1卷 第1期 页码 52-61 doi: 10.15302/J-FEM-2014008
关键词： government-led construction project urban complex meta-synthesis management sustainable development benefit maximization
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《医学前沿（英文）》 2012年 第6卷 第1期 页码 94-99 doi: 10.1007/s11684-012-0181-y
Systematic reviews and meta-analyses are playing an increasingly important role in clinical research and practice. This study aimed to measure the scientific production of systematic review and meta-analysis from the three major regions of China: the Mainland (ML), Hong Kong (HK), and Taiwan (TW). English articles on systematic review and meta-analysis from ML, HK, and TW from 2001 to 2010 were retrieved from the PubMed database. The total number of articles, impact factors (IF), and articles published in high-impact journals were conducted for quantity and quality comparisons among the three regions. There were 1 587 published articles from ML (1 292), HK (203), and TW (92) during the past ten years. The annual total numbers of articles in the three regions increased significantly from 2001 to 2010 (from 13 to 677). The number of articles from ML has exceeded that from TW since 2001, and surpassed that from HK in 2003. The accumulated IF of articles from ML (3 488.24) was higher than those from HK (493.16) and TW (216.39). HK had the highest average IF of 3.31, followed by ML of 2.90 and TW of 2.85. Researchers from HK published a larger proportion of papers in high-impact journals than those from ML and TW. The Cochrane Database of Systematic Reviews was the most popular journal in China. Chinese authors have been very active to enhance the systematic review and meta-analysis research over the past ten years, especially in ML. The gap between ML and the other two regions has been narrowed. But there is still considerable room for Chinese authors to improve their studies on systematic review and meta-analysis.
关键词： systematic review meta-analysis China Chinese impact factor
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《医学前沿（英文）》 2013年 第7卷 第4期 页码 499-505 doi: 10.1007/s11684-013-0296-9
Pancreatic fistula (PF) is the most frequent complication after distal pancreatectomy (DP). Prophylactic transpapillary pancreatic stenting (PTPS) has been proposed recently for the prevention of PF after DP. In this meta-analysis, a comprehensive search was performed in the PubMed, Embase, and Cochrane Library databases. Studies analyzing the results of PTPS in DP were considered eligible for this meta-analysis. The analyzed outcome variables included PF rate, postoperative morbidity, non-PF-related complications, mortality, operation duration, and hospital stay. Four studies with 200 patients were included in this review. Only one was a randomized controlled trial (RCT). The results showed that PTPS was associated with less PF formation (odds ratio, 0.45; 95% confidence interval [CI], 0.22–0.94; P = 0.03) and shorter hospital stay (mean difference, -6.31; 95% CI, -6.99 to -5.62; P<0.00001). There was no significant difference in terms of the other variables. In conclusion, current evidence indicates that PTPS could reduce PF incidence and hospital stay after DP, without increasing other complications or operative time. However, the evidence is not solid, because the single RCT conflicted with the other three retrospective reports. Thus, considering the limitation, more well-designed RCTs on this topic are needed in the future.
关键词： pancreatic fistula distal pancreatectomy pancreatic stent meta-analysis
Radical versus conservative surgical treatment of liver hydatid cysts: a meta-analysis
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《医学前沿（英文）》 2018年 第12卷 第3期 页码 350-359 doi: 10.1007/s11684-017-0559-y
To date, the efficacy of radical surgery (RS) versus conservative surgery (CS) for liver hydatid cysts (LHC) remains controversial. This meta-analysis was conducted to compare the two interventions. PubMed, Embase, and Web of Science were searched from their inceptions until June 2016. Meta-analysis was performed using STATA 12.0 software. We identified 19 eligible studies from 10 countries by retrieval. In total, 1853 LHC patients who received RS were compared with 2274 patients treated by CS. The risk of postoperative overall complication, biliary fistula, and recurrence was significantly lower, and operation time was significantly longer in the RS group. However, no statistically significant differences were found in terms of mortality risk and the duration of hospital stay between RS and CS. No significant publication biases were observed in all the above analyses. In conclusion, RS reduces the rates of postoperative complications and recurrence, whereas no trend toward such a reduction in mortality was observed in LHC patients.
关键词： liver hydatid cysts radical surgery conservative surgery meta-analysis complications
Hong-feng Chai,Quan Sun
《工程管理前沿（英文）》 2016年 第3卷 第4期 页码 404-413 doi: 10.15302/J-FEM-2016037
关键词： financial information system meta-synthesis methodology bank card information exchange
Hamed FATHNEJAT, Behrouz AHMADI-NEDUSHAN
《结构与土木工程前沿（英文）》 2020年 第14卷 第4期 页码 907-929 doi: 10.1007/s11709-020-0628-1
关键词： two-stage method modal strain energy surrogate model GMDH optimization damage detection
钱振业,杨广耀,韦德森,程玲珠
《中国工程科学》 2006年 第8卷 第12期 页码 10-15
中国要不要搞载人航天？怎么搞载人航天？采取何种发展战略和技术途径，涉及政治、经济、军事、社会和科技诸多方面。遵照钱学森院士创建的系统学提出的“定性与定量相结合的综合集成方法”，结合中国国情，以软科学命题，从指导思想、研究步骤和研究方法几方面进行了研究，研究结果表明，“面对世界载人航天的挑战和机遇，中国载人航天不可不搞，也不能大搞，飞船起步，平稳发展万无一失。盲自赶超或急于缩小差距均将陷入困境，疑虑过多以至坐视不顾，也会失掉机会和希望。”文章对该软科学命题做了总结。
标题 作者 时间 类型 操作
HAPE3D—a new constructive algorithm for the 3D irregular packing problem
Xiao LIU,Jia-min LIU,An-xi CAO,Zhuang-le YAO
期刊论文
Efficacy and safety of benralizumab in patients with eosinophilic asthma: a meta-analysis of randomized
null
期刊论文
Association between telomere length and survival in cancer patients: a meta-analysis and review of literature
null
期刊论文
Treatment outcomes of pulmonary tuberculosis in the past decade in the mainland of China: a meta-analysis
null
期刊论文
Chinese medicine combined with Western therapy on primary hepatic carcinoma: a systematic review with meta-analysis
null
期刊论文
Research and Practice of Meta-synthesis Management for the Government-led Urban Complex Construction
Ru-gui Chen,Jia-meng Chen
期刊论文
Scientific publications on systematic review and meta-analysis from Chinese authors: a 10-year survey
null
期刊论文
The role of prophylactic transpapillary pancreatic stenting in distal pancreatectomy: a meta-analysis
null
期刊论文
on the Giant and Complex Financial Information System Engineering Management from the Perspective of Meta-synthesis
Hong-feng Chai,Quan Sun
期刊论文
An efficient two-stage approach for structural damage detection using meta-heuristic algorithms and group
Hamed FATHNEJAT, Behrouz AHMADI-NEDUSHAN
期刊论文
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